We are committed to cutting-edge investigations involving basic science, translational and clinical research. Our main areas of focus include the following:
3D printing and tissue engineering for airway reconstruction
Through our tissue engineering research program, we're aiming to fabricate a 3D printed, tissue engineered scaffold for airway reconstruction. Our ultimate goal is to produce a long segment tracheal replacement graft. We have multiple projects looking at various aspects, including in vitro and in vivo studies. This activity is funded through private grants and awards and has already resulted in multiple publications and presentations at national and international scientific meetings.
Our vascular anomalies program studies rare head and neck tumors and malformations. Our long-term goal is to use specimens collected in our tissue bank biorepository to study the cause of these diseases, so we can better target therapeutics as well as determine biomarkers for treatment response.
Our multidisciplinary velopharyngeal insufficiency (VPI) program is aimed at outcomes research. The pediatric otolaryngology team works side by side with the speech and language pathology team to determine the long-term effect of surgery and therapy on speech.
Recurrent laryngeal nerve function and laryngeal dysfunction research program
In a basic science model, we are currently studying reinnervation of the larynx using a rat model to more efficiently regain function of the recurrent laryngeal nerve to allow vocal fold movement. The experiments have translated to a number of clinical applications including potential reversal of laryngospasm, which can prevent death. This work is NIH-funded.